年产700吨对硝基苯乙酮车间的工艺初步设计

北京理工大学珠海学院2020届本科生毕业设计Preliminary Design of Process for a 700-ton P-nitrophenylacetoneWorkshopAbstractP-nitrophenylacetone,also known as 4-nitrophenylacetone,is a pure light yellow crystal,soluble in benzene,ether,hot ethanol but insoluble in water.It is an important organicsynthesis intermediate for the production of chloramphenicol.The process uses nitrificationand oxidation,compared with other synthetic processes,the advantages of this process is:starting material ethylbenzene easy to obtain It is easy to control and the reaction iscontinuous,and there are few by-products to form p-nitrophenylacetone.Keywords:p-nitroacetophenone chloramphenicol Nitrification and oxidation ofethylbenzene