年产1000万支重组人干扰素α-2b原液生产车间工艺设计

Process Design of Raw liquid production Workshop with an Annualoutput of 10 million Recombinant Human Interferon a-2bABSTRACTInterferon is a kind of protein with anti-cell division and immunomodulatory function.According to the cell structure and source can be divided into a BY three types.Amongthem,modern research has proved that interferon a -2b has obvious clinical effect in thetreatment of tumor,fungal skin disease,rheumatoid arthritis and other diseases.The inclusionbody was obtained by using recombinant E.coli culture,and the inclusion body was purified bycomplex purification.From the original liquid can be made into injection,powder,gel,suppository,pills and other dosage forms,the market prospects are wide.Based on the research on the preparation and purification of recombinant human interferon inrecent years,an annual production workshop a-2b 10 million recombinant human interferonwas designed.Key words:laminar analysis stoste fermentert plant design IFN a 2b