微波消融热疗中靶区组织升温特性的影响因素数值模拟

(论文)Numerical Simulation of the Factors Influencing theTemperature Rise Characteristics of Target Tissue inMicrowave Ablation HyperthermiaAbstractWith the development of society,what we often hear recently is that cancer isbecoming younger and more common.According to the survey,the number ofpeople suffering from cancer in the world is "increasing year by year",and thenumber of people who die of this disease is also rising every year.In 2018 alone,there were about 18.1 million more patients,and about 9.6 million people died.Until now,cancer is still the most difficult problem to prolong the average lifespan of human beings.In recent years,numerous scholars and experts have beendevoting themselves to research and work hard,and walked out of the innovativepath of local ablation.Once the technology was launched,it has attracted greatattention.After more than ten years of development,it has shown great value inclinical applied medicine.Microwave ablation plays a more and more importantrole in tumor treatment,especially in the treatment of liver cancer,microwaveablation has become a very common treatment.However,there are still manyproblems to be solved in the process of ablation,including some key technologiessuch as temperature field distribution,power and time control selection,amongwhich temperature field distribution is one of the important research directions inthe field of microwave ablation.The distribution of temperature field and theshape of ablation area are the key to ensure the effect of microwave ablation.In this paper,the prediction and Simulation of the effect of microwaveablation will be simulated by computer,by using COMSOL multiphysics 5.4multi physical field simulation software can simulate the change of effectiveablation area size and ablation temperature in the process of microwave ablationby microwave power,frequency and time,tissue physical parameters and addingsensitizing materials,so as to obtain more accurate temperature field distributionlaw and provide reference for clinical application of microwave ablation.In this paper,we also add the sensitizing material sodium alginate pellet tothe target model to simulate the effect of the sensitizing material on themicrowave ablation.The results show that the addition of sodium alginate has asignificant effect on increasing the effective ablation volume.In the process of model building,the grid independence is proved,and thegrid independent model is selected for simulation,which proves that the physical.Ⅱ-