年产2亿粒双氯芬酸钠双释放肠溶胶囊生产车间设计

北京理工大学珠海学院2020届本科生毕业设计Design of workshop for annual production of 200 million diclofenacsodium double-release enteric-coated capsulesAbstractDiclofenac sodium can be made into a variety of dosage forms in clinical applications.Commonly used suppositories,enteric-coated tablets,sustained-release tablets,sustained-releasecapsules,creams,gels,eye drops,etc.In this design,diclofenac sodium is made into double-releaseenteric capsules,which has a faster effect than ordinary slow-release preparations,while maintaining along duration of action,can quickly relieve pain symptoms,good individual repeatability,can promotecartilage proteoglycan metabolism,prevent Long-term complications occur,and the amount oftreatmentdiffers greatly from the amount of poisoning,thereby ensuring that the treatment is not only effective,but also safe and reliable,and meets the long-term treatment needs of patients.This design complies with the relevant provisions of the design of the relevant phammaceuticalfactory,and completed the workshop design of 200 million diclofenac sodium double-release enteric-coated capsules.The design includes process flow design,material balance calculation,equipmentselection,economic balance calculation,plant layout,clean area design,and "Three Wastes"treatmentaccording to the above route to complete this design.Keywords:Diclofenac sodium,Double-release enteric-coated capsules,Workshop designIV