白芸豆提取物有效成分及药理作用研究进展

白芸豆提取物有效成分及药理作用研究进展目录（综述）摘要…Abstract……………………引言…………61白芸豆概述……,71.1白芸豆简介……71.2白芸豆的营养价值、药用价值1.2.1营养价值71.2.2药用价值.71.3白芸豆的加工利用现状……………82白芸豆的主要药理作用……82.1降低血糖、血脂…2.2抗氧化作用……………………82.3抗炎作用……92.4调节肠道微生物……93白芸豆有效成分研究进展…103.1多酚类………………………103.2糖蛋白……………103.3多糖………………………………103.3.1果胶………103.3.2膳食纤维..…114白芸豆治疗相关疾病中的应用……114.1糖尿病……………114.2肥胖………………………124.3癌症……………………124.4结肠炎…1345肝脂肪病……………134.6高脂血症………134.7避孕及抗早孕…145白芸豆的使用注意事项………………14结语………………15参考文献……………16致谢…201摘要白芸豆(Phaseolus vulgaris Linn..)为豆科(Leguminosae sp.)菜豆属植物，一年生、缠绕或近直立草本，在全世界范围内广泛种植，是我国重要的经济豆类之一。通过中国知网、万方、Pubmed等数据库，检索了近20年来国内外报道白芸豆的相关文献。有研究表明，白芸豆含有较多的蛋白质、膳食纤维、微量元素以及少量的脂肪，有降低血糖和血脂、调节肠道微生物群、改善胰岛素抵抗、抗氧化、抗炎和抗菌等药理作用，在临床上主要被用于治疗结肠炎、肥胖、糖尿病、高脂血症和癌症等疾病。但目前针对白芸豆的基础研究仍比较少，制约了我国白芸豆产业向医药领域的发展。鉴于此，本文系统归纳了白芸豆提取物的成分类型、药理作用以及临床应用，为更深入研究白芸豆的物质基础提供理论参考，以期后续研发出白芸豆的保健食品和创新药。关键词：白芸豆；有效成分；药理作用；糖尿病2AbstractWhite kidney bean (Phaseolus vulgaris Linn.)is an annual,twined or nearly erect herb ofLeguminosae sp.It is widely cultivated all over the world and is one of the important economiclegumes in China.Through CNKI,Wanfang,Pubmed and other databases,the literatures onwhite kidney bean in recent 20 years at home and abroad were searched.Studies have shownthat white kidney beans contain more protein,dietary fiber,trace elements and a small amountof fat,have the pharmacological effects of reducing blood sugar and blood lipids,regulatingintestinal microbiota,improving insulin resistance,antioxidant,anti-inflammatory andantibacterial,and are mainly used in clinical treatment of colitis,obesity,diabetes,hyperlipidemia and cancer and other diseases.But at present,the basic research on white kidneybean is still relatively small,which restricts the development of white kidney bean industry tomedicine field in our country.In view of this,this paper systematically summarized thecomposition types,pharmacological effects and clinical applications of white kidney beanextract,to provide theoretical reference for further research on the material basis of whitekidney bean,in order to develop health food and innovative drugs of white kidney bean.Key Words:White kidney beans;Active ingredient;Pharmacological effect;Diabetesmellitus;3