左卡尼汀用于治疗扩张性心肌病的疗效观察及血药浓度监测

青岛大学硕士学位论文解患者病情，对于改善扩张型心肌病患者的症状具有积极的意义。左卡尼汀可以增加心肌细胞的功能，减少负性变化，从而减少心血管不良事件的发生，对患者的预后有积极意义。关键词：左卡尼汀扩张型心肌病血药浓度Objective:To observe the patients with dilated cardiomyopathy clinical treatment,plusleft-handed Carney Dean L-carnitine,L-CN )patient's condition change and the serumconcentrations in patients with case.To explore Levocarnitine for the efficacy of dilatedcardiomyopathy,while observing the content of the blood concentration of its beforeand after administration of L-carnitine,which further determine the effect oflevocarnitine in the treatment of dilated cardiomyopathy,explore the left Carney Ting ofthe correlation between plasma concentration and the improvement of heart functionindicators.Methods:the School Affiliated Hospital in 2008February to2011February betweenoutpatient and inpatient treatment in patients with dilated cardiomyopathy in 30patients,all patients were confirmed by clinical and imaging diagnosis of diagnosed asdilated cardiomyopathy,all the patients were randomly divided into observation groupand control group each 15 people.The control group used the cardiology dilatedcardiomyopathy patients given routine treatment,cause and symptomatic treatment,limiting intake of salt,use of diuretics,ACEl class of drugs,digitalis cardiac drugs,vasodilators,detection of patients'vital signs,pay close attention to the change of thepatient's condition,the unexpected situation promptly notify the attending physician,immediate symptomatic processing;the observation group in the use of Cardiologydilated cardiomyopathy on the basis of conventional therapy,combined withlevocarnitine therapy,were compared between the two groups before and after thetreatment in left ventricular end diastolic diameter left ventricular end diastolicdiameter,LVEDD )Left ventricular ejection fraction LEFTVENTRICULAR ejection fraction,LVEF )Fractional shortening fractional shortening,FS )NYHA changes in cardiacfunction classification.Detection of the observation group used L-carnitine after blood