还原型氧化石墨烯_银纳米粒子修饰电极检测多巴胺

AbstractIn recent years,with the development of the times and the gradual improvement ofpeople's living standards,people's attention to physical health has become increasinglyhigh,and disease prevention has become a highly valued aspect.Dopamine (DA)is a veryimportant neurotransmitter that plays a significant role in regulating emotions and thecentral nervous system.Therefore,the detection of DA is crucial.Graphene,as a newmaterial,has become the current hot spot because of its excellent performance.Based onthe reduced Graphite oxide modified glassy carbon electrode,silver nanoparticles weremodified to prepare the sensor.Ag nanoparticles (Ag-NPs)have good conductivity andbiocompatibility,which can greatly improve the migration rate of electrode Surface charge,effectively improve the electrochemical response signal,and improve the sensitivity of thesensor when applied to the electrochemical sensor.Reduced Graphite oxide (rGO)andAg-NPs can significantly increase the current signal of the sensor,so the detectionsensitivity can be improved.In the experiment,the Graphite oxide (GO)modifiedelectrode was first prepared,then it was reduced to rGO by electrochemical method,andfinally Ag nanoparticles were modified by drip coating to obtain GCE/rGO/Ag NPsmodified electrode.Graphite oxide and reduced Graphite oxide were characterized byinfrared spectroscopy and Scanning electron microscope.Cyclic voltammetry (CV)is usedto optimize the optimal pH conditions and scanning rate conditions for the detection of DA;Using CV to detect a series of DA solutions with different concentrations,the linear rangeof DA obtained is:2 u M-100 u M.Since the DA sample often contains small biologicalmolecules such as uric acid (UA),the anti-interference ability of DA was tested by linearscanning Voltammetry (LSV).The results showed that the determination of DA wasfeasible in the presence of small biological molecules such as UA.Key Words:Silver nanoparticles;Modified electrode;Dopamine;Graphene