2021-2022年某院细菌药性监测结果与分析

AbstractObjective:To provide a basis for clinical treatment and formulation of hospital infection controlmeasures,and to monitor and analyze the sensitivity and drug resistance of clinically isolatedpathogens to commonly used antibiotics.Methods The clinical isolates were statisticallyanalyzed by retrospective investigation.The pathogenic microorganisms were tested and thedrug sensitivity test of sputum,urine and other specimens was carried out to analyze the drugsensitivity results.Results A total of 3307 non-repetitive pathogenic strains except fungiwere detected,of which 1840(55.64 %)were multidrug-resistant bacteria.The source ofpathogenic bacteria was mainly sputum and urine.The most pathogenic bacteria were detected inpatients aged 50-69 years.The three departments with the most detected pathogens were thesecond department of neurology,respiratory medicine and the first department of neurology.Klebsiella pneumoniae and its multi-drug resistant bacteria ESBLs and CRKPN were highlysensitive to tetracycline tigecycline.Highly sensitive to aminoglycoside amikacin Pseudomonasaeruginosa and its multi-drug resistant bacteria CRPAE proteus mirabilis and its multi-drugresistant bacteria ESBLs are highly sensitive to carbapenem meropenem,while its CRE is notsensitive to all types of antibiotics.Acinetobacter baumannii and its multi-drug resistant bacteriaCRAB were highly sensitive to tetracycline tigecycline and minocycline.Escherichia coli has ahigh sensitivity to carbapenems,and its multi-drug resistant bacteria ESBLs are sensitive to mostantibiotics.Staphylococcus aureus was 100%sensitive to glycopeptides and rifamycins,and itsmulti-drug resistant bacteria MRAS was completely resistant to penicillins.Conclusion Thesituation of bacterial resistance in this hospital is severe,and the rational use of antibiotics mustbe further standardized.Keywords bacterial resistance;detection;antibiotics rational use女